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Postdoctoral Fellow — Monocyte Biology and Cancer Vaccine Immunology
FengLab · Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences · Hangzhou, China
We are recruiting a postdoctoral fellow for a newly funded National Natural Science Foundation of China project investigating how monocyte baseline immune states regulate vaccine-specific T cell differentiation and function.
The project uses nucleic acid cancer vaccines as a model to connect human immune variation with mechanisms of vaccine response. It combines human cohort profiling, single-cell multi-omics, and mechanistic experiments in mouse models to understand how monocytes shape T cell priming, differentiation, and antitumor function.
What you will work on
- Characterize monocyte immune states and their relationships with vaccine-induced T cell responses.
- Investigate antigen presentation, costimulatory signals, and cytokine pathways through cellular assays and genetic or pharmacological perturbations.
- Test mechanisms in mouse tumor and vaccination models, measuring T cell differentiation, function, and antitumor responses.
- Collaborate on the interpretation of single-cell and multi-omics data, and contribute to study design and manuscript preparation.
Who should apply
- A PhD awarded within the past 12 months at the time of application, in immunology, molecular or cell biology, or a closely related field.
- A strong interest in monocyte biology, T cell immunity, or cancer vaccines, with experience designing and conducting mechanistic biological experiments.
- Relevant skills in one or more areas: flow cytometry, immune cell isolation and culture, T cell functional assays, mouse models, or molecular perturbation approaches.
- Experience with single-cell RNA-seq, chromatin accessibility analysis, or computational immunology is an advantage.
- The ability to work independently and collaboratively, maintain rigorous research records, and communicate findings clearly.
The project offers the opportunity to connect human systems immunology with experimental mechanism through the institute’s flow cytometry, single-cell and multi-omics, computational, and animal research platforms.
To apply: Email fengyupeng@him.cas.cn with the subject “Postdoc application — Monocyte and T cell immunity”. Include the materials below, your PhD award date, and your earliest available start date.
How to apply
Please send the following:
- A curriculum vitae
- A brief description of your research interests
- Relevant publications or research experience
- Contact information for references